冠状动脉狭窄情况下的非牛顿血液流动和大分子传质

李新宇; 温功碧; 李丁

冠状动脉狭窄情况下的非牛顿血液流动和大分子传质

北京大学力学和工程科学系, 湍流研究国家重点实验室, 北京100871

基金项目: 国家自然科学基金重点资助项目(19732003)

详细信息

作者简介:
李新宇(1971- ),男,辽宁沈阳人,硕士.

中图分类号: R318.01
计量
- 文章访问数: 2143
- HTML全文浏览量: 48
- PDF下载量: 714
- 被引次数: 0
出版历程
- 收稿日期: 1999-08-12
- 修回日期: 2000-07-16
- 刊出日期: 2001-04-15

Computer Simulation of Non-Newtonian Flow and Mass Transport Through Coronary Arterial Stenosis

Mechanics and Engineering Science Department, Peking University, Beijing 100871, P R China

摘要

摘要: 针对冠状动脉狭窄的情况,采用数值模拟方法求解了牛顿流体与非牛顿流体(幂次律流体和Casson流体)的定常与脉动的流场。在此基础上,求解了LDL(低密度脂肪蛋白)和Albumin(血清白蛋白)的浓度场。根据计算结果,详细讨论了壁面剪应力、非牛顿流效应、分子大小等因素对大分子传质的影响;并对牛顿流体与非牛顿流体、定常流动与脉动流动的大分子浓度场进行了比较,这些结果对于了解动脉硬化成因与流动特性和大分子传质的联系提供了较为丰富的信息。
- 动脉粥样硬化 /
- 非牛顿流 /
- 大分子传质 /
- 壁面剪应力
Abstract: A numerical analysis of Newtonian and non-Newtonian flow in an axi-symmetric tube with a local constriction simulating a stenosed artery under steady and pulsatile flow conditions was carried out.Based on these results,the concentration fields of LDL(low-density lipoprotein)and Albumin were discussed.According to the results,in great details the macromolecule transport influences of wall shear stress,non-Newtonian fluid character and the scale of the molecule etc are given.The results of Newtonian fluid flow and non-Newtonian fluid flow,steady flow and pulsatile flow are compared.These investigations can provide much valuable information about the correlation between the flow properties,the macromolecule transport and the development of atherosclerosis.
- atherosclerosis /
- non-Newtonian fluid flow /
- macromolecule transport /
- wall shear stress

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参考文献(17)

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