Research on the Separation Characteristics of Microplastic Particles in Straight-Channel Bionic Microfluidic Chips
-
摘要:
为优化一种高效仿生微流控芯片，实现微塑料等微米级颗粒的高效、高通量分离，采用计算流体动力学与离散元耦合（CFD-DEM）的数值方法，对一种仿生微流控过滤结构的内部流场及颗粒分离机理进行了系统研究.研究总结了4种有趣的颗粒分离机理：低Reynolds数下，颗粒通过惯性聚焦效应进行分离；高Reynolds数下，颗粒依靠瓣膜前缘涡旋的捕获作用和通道末端瓣膜间的回流作用形成3种分离机理.最后，基于机理分析对芯片进行结构优化，通过增大副通道截面长度，实现了颗粒分离效率7.9%的最高提升，主通道流量占比平均降低7.2%，并使干净滤液产出最高增加9.4%.这些发现为高效仿生过滤膜的优化设计提供了理论支撑.
Abstract:To optimize an efficient biomimetic microfluidic chip for the highefficiency, highthroughput separation of micronsized particles such as microplastics, a computational fluid dynamic (CFD) coupled with discrete element method (DEM) numerical approach was employed to systematically investigate the internal flow field and particle separation mechanisms of a biomimetic microfluidic filtration structure. The 4 interesting particle separation mechanisms were summarized: at low Reynolds numbers, particles are separated through inertial focusing effects; at high Reynolds numbers, particles rely on the capture effect of vortices at the leading edge of the valve and the backflow effect between valves at the channel end to form 3 separation mechanisms. Finally, based on the mechanism analysis, the chip structure was optimized by increasing the crosssectional length of the auxiliary channel, to achieve a maximum improvement of 7.9% in particle separation efficiency, an average reduction of 7.2% in the main channel flow rate, and a maximum increase of 9.4% in the production of clean filtrate. These findings provide a theoretical support for the optimized design of efficient bionic filtration membranes.
-
Key words:
- microfluidics /
- bionic structure /
- microplastic particle /
- particle filtration /
- CFD-DEM
-
ZURI G, KARANASIOU A, LACORTE S. Human biomonitoring of microplastics and health implications: a review[J].Environmental Research,2023,237: 116966. [2]CABA-FLORES M D, MARTNEZ-VALENZUELA C, CRDENAS-TUEME M, et al. Micro problems with macro consequences: accumulation of persistent organic pollutants and microplastics in human breast milk and in human milk substitutes[J].Environmental Science and Pollution Research,2023,30(42): 95139-95154. [3]MA J, WU Y, LIU Y, et al. Cell-sorting centrifugal microfluidic chip with a flow rectifier[J].Lab on a Chip,2021,21(11): 2129-2141. [4]XIANG N, LI Q, NI Z. Combining inertial microfluidics with cross-flow filtration for high-fold and high-throughput passive volume reduction[J].Analytical Chemistry,2020,92(9): 6770-6776. [5]AHMED H, RAMESAN S, LEE L, et al. On-chip generation of vortical flows for microfluidic centrifugation[J].Small,2020,16(9): 1903605. [6]DI CARLO D, IRIMIA D, TOMPKINS R G, et al. Continuous inertial focusing, ordering, and separation of particles in microchannels[J].Proceedings of the National Academy of Sciences of the United States of America,2007,104(48): 18892-18897. [7]KUMAR T, HARISH A V, ETCHEVERRY S, et al. Lab-in-a-fiber-based integrated particle separation and counting[J].Lab on a Chip,2023,23(9): 2286-2293. [8]ZHANG P, BACHMAN H, OZCELIK A, et al. Acoustic microfluidics[J].Annual Review of Analytical Chemistry,2020,13: 17-43. [9]PAI P, ZANDRINI T, VZQUEZ R M, et al. Particle manipulation by optical forces in microfluidic devices[J].Micromachines,2018,9(5): 200. [10]DING X, PENG Z, LINS S, et al. Cell separation using tilted-angle standing surface acoustic waves[J].Proceedings of the National Academy of Sciences of the United States of America,2014,111(36): 12992-12997. [11]SEGR G, SILBERBERG A. Radial particle displacements in Poiseuille flow of suspensions[J].Nature,1961,189(4760): 209-210. [12]王企鲲, 孙仁. 管流中颗粒“惯性聚集”现象的研究进展及其在微流动中的应用[J]. 力学进展, 2012,42(6): 692-703.(WANG Qikun, SUN Ren. Advances in the research on “inertial focus of particles” and its application in microfluidics[J].Advances in Mechanics,2012,42(6): 692-703. (in Chinese)) [13]沈洋, 王企鲲, 刘唐京. 剪切稀化流变特性对微通道中颗粒迁移的影响[J]. 应用数学和力学, 2024,45(5): 637-650.(SHEN Yang, WANG Qikun, LIU Tangjing. Effect of shear thinning rheological properties on particle migration in microchannels[J].Applied Mathematics and Mechanics,2024,45(5): 637-650. (in Chinese)) [14]赵可馨, 王企鲲, 柯灵杰. 微通道中流体弹性对颗粒聚集的影响[J]. 应用数学和力学, 2025,46(10): 1256-1266.(ZHAO Kexin, WANG Qikun, KE Lingjie. The influence effect of fluid elasticity on particle aggregation in microchannels[J].Applied Mathematics and Mechanics,2025,46(10): 1256-1266. (in Chinese)) [15]AMINI H, LEE W, DI CARLO D. Inertial microfluidic physics[J].Lab on a Chip,2014,14(15): 2739-2761. [16]DI CARLO D, EDD J F, HUMPHRY K J, et al. Particle segregation and dynamics in confined flows[J].Physical Review Letters,2009,102(9): 094503. [17]董骅, 黄龙润, 范亮亮, 等. 弧形变截面微通道内颗粒富集的实验研究[J]. 工程热物理学报, 2025,46(2): 486-490.(DONG Hua, HUANG Longrun, FAN Liangliang, et al. Experimental study on particle enrichment in arc-shaped variable cross-section microchannels[J].Journal of Engineering Thermophysics,2025,46(2): 486-490. (in Chinese)) [18]ZHAO Q, YUAN D, ZHANG J, et al. A review of secondary flow in inertial microfluidics[J].Micromachines,2020,11(5): 461. [19]白汉洁, 林智慧, 郭时超, 等. 螺旋通道中稳定增强的二次流构建及其粒子聚焦研究[J]. 分析化学, 2024,52(4): 504-512.(BAI Hanjie, LIN Zhihui, GUO Shichao, et al. Spiral microfluidic for particle focusing by stabilization and acceleration of secondary flow[J].Chinese Journal of Analytical Chemistry,2024,52(4): 504-512. (in Chinese)) [20]DIVI R V, STROTHER J A, MISTY PAIG-TRAN E W. Manta rays feed using ricochet separation, a novel nonclogging filtration mechanism[J].Science Advances,2018,4(9): eaat9533. [21]CLARK A S, SAN-MIGUEL A. A bioinspired, passive microfluidic lobe filtration system[J].Lab on a Chip,2021,21(19): 3762-3774. [22]HASHEMI SHAHRAKI Z, NAVIDBAKHSH M, TAYLOR R A. Inertial cell sorting of microparticle-laden flows:an innovative OpenFOAM-based arbitrary Lagrangian-Eulerian numerical approach[J].Biomicrofluidics,2021,15(1): 014111. [23]TSUJI Y, TANAKA T, ISHIDA T. Lagrangian numerical simulation of plug flow of cohesionless particles in a horizontal pipe[J].Powder Technology,1992,71(3): 239-250. -
计量
- 文章访问数: 36
- HTML全文浏览量: 5
- PDF下载量: 9
- 被引次数: 0
下载:
渝公网安备50010802005915号